Enantioseparations with the macrocyclic antibiotic ristocetin a using a countercurrent process in CE

Chirality ◽  
1999 ◽  
Vol 11 (8) ◽  
pp. 663-668 ◽  
Author(s):  
Tanya M. Oswald ◽  
Timothy J. Ward
Keyword(s):  
Macrocyclic Antibiotic ◽  
Ristocetin A ◽  
Countercurrent Process

Convenient Synthesis of the Central 3,6-Di(2-thiazolyl)-2-(4-thiazolyl)pyridine Skeleton of a Macrocyclic Antibiotic, GE 2270 A

1998 ◽  
Vol 71 (8) ◽  
pp. 1863-1870 ◽  
Author(s):  
Kazuo Okumura ◽  
Hiroyuki Saito ◽  
Chung-gi Shin ◽  
Kazuyuki Umemura ◽  
Juji Yoshimura
Keyword(s):  
Macrocyclic Antibiotic ◽  
Convenient Synthesis

scholarly journals Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3527
Author(s):  
Ali Fouad ◽  
Adel A. Marzouk ◽  
Montaser Sh. A. Shaykoon ◽  
Samy M. Ibrahim ◽  
Sobhy M. El-Adl ◽  
...  
Keyword(s):  
Glycidyl Methacrylate ◽  
Chiral Stationary Phase ◽  
Reversed Phase ◽  
Chiral Selector ◽  
Antifungal Drugs ◽  
Organic Polymer ◽  
Rp Hplc ◽  
Macrocyclic Antibiotic ◽  
Adrenergic Blockers ◽  
H1 Blockers

Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer monolithic capillary. The latter is prepared using the copolymerization of the monomers glycidyl methacrylate (GMA) and ethylene glycol dimethacrylate (EGDMA) in the presence of daptomycin in water. Under reversed phase conditions (RP), the prepared capillaries were tested for the enantioselective nanoliquid chromatographic separation of fifty of the racemic drugs of different pharmacological groups, such as adrenergic blockers, H1-blockers, NSAIDs, antifungal drugs, and others. Baseline separation was attained for many drugs under RP-HPLC. Daptomycin expands the horizon of chiral selectors in HPLC.

Unusual Difference in Enantioselectivity of Two Chiral Stationary Phases with Grafted Antibiotic Ristocetin A

2021 ◽  
Vol 84 (3) ◽  
pp. 307-311
Author(s):  
Margarita V. Kopchenova ◽  
Maria V. Stepanova ◽  
Leonid D. Asnin
Keyword(s):  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Ristocetin A

ChemInform Abstract: STRUCTURAL STUDIES OF RISTOCETIN A (RISTOMYCIN A): CARBOHYDRATE-AGLYCONE LINKAGES

1981 ◽  
Vol 12 (8) ◽  
Author(s):  
F. SZTARICSKAI ◽  
C. M. HARRIS ◽  
A. NESZMELYI ◽  
T. M. HARRIS
Keyword(s):  
Structural Studies ◽  
Ristocetin A

scholarly journals Structure of Ristocetin A

1972 ◽  
Vol 69 (9) ◽  
pp. 2420-2421 ◽  
Author(s):  
J. R. Fehlner ◽  
R. E. J. Hutchinson ◽  
D. S. Tarbell ◽  
J. R. Schenck
Keyword(s):  
Ristocetin A

scholarly journals Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A

2018 ◽  
Vol 57 (34) ◽  
pp. 11020-11024 ◽  
Author(s):  
Hiromu Hattori ◽  
Joel Roesslein ◽  
Patrick Caspers ◽  
Katja Zerbe ◽  
Hideki Miyatake-Ondozabal ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Macrocyclic Antibiotic ◽  
Synthesis And Biological Evaluation
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